G93.41 Metabolic encephalopathy

Billable ICD-10-CM code, FY2026. Acts as a Major Complication or Comorbidity (MCC) as a secondary diagnosis.

Applicable to

• Septic encephalopathy

Applies from G93.4 Other and unspecified encephalopathy

Excludes2 (not included here)

• alcoholic encephalopathy (G31.2)
• encephalopathy in diseases classified elsewhere (G94)
• hypertensive encephalopathy (I67.4)
• toxic (metabolic) encephalopathy (G92.8)

MS-DRG index

Defines the logic of DRG(s) 070-072 in MDC 01.

Approximate ICD-9-CM (GEMs)

• 348.31 Metabolic encephalopathy

Code annotations containing back-references to G93.41

Back-references to G93.41

• Use Additional: M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA] ("encephalopathy (metabolic) (septic) (G93.41)")
• Use Additional: R65.11 Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction ("encephalopathy (metabolic) (septic) (G93.41)")
• Use Additional: R65.2 Severe sepsis ("encephalopathy (metabolic) (septic) (G93.41)")

Back-references to G93.4

• Code Also: F78.A1 SYNGAP1-related intellectual disability ("encephalopathy (G93.4-)")

Diagnosis Index entries for G93.41

• Encephalopathy (acute) › metabolic
• Encephalopathy (acute) › septic

Nearby codes

• G93.31 Postviral fatigue syndrome
• G93.32 Myalgic encephalomyelitis/chronic fatigue syndrome
• G93.39 Other post infection and related fatigue syndromes
• G93.4 Other and unspecified encephalopathy
• G93.40 Encephalopathy, unspecified
• G93.41 Metabolic encephalopathy (this code)
• G93.42 Megalencephalic leukoencephalopathy with subcortical cysts
• G93.43 Leukoencephalopathy with calcifications and cysts
• G93.44 Adult-onset leukodystrophy with axonal spheroids
• G93.45 Developmental and epileptic encephalopathy
• G93.49 Other encephalopathy