E78.1 Pure hyperglyceridemia

Billable ICD-10-CM code, FY2026.

Applicable to

• Elevated fasting triglycerides
• Endogenous hyperglyceridemia
• Fredrickson's hyperlipoproteinemia, type IV
• Hyperlipidemia, group B
• Hyperprebetalipoproteinemia
• Very-low-density-lipoprotein-type [VLDL] hyperlipoproteinemia

Applies from E78 Disorders of lipoprotein metabolism and other lipidemias

Excludes1 (never code together)

• sphingolipidosis (E75.0-E75.3)

Risk adjustment (HCC)

• RxHCC V08: HCC 47 — Disorders of Lipoid Metabolism

MS-DRG index

Defines the logic of DRG(s) 642 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 272.1 Pure hyperglyceridemia

Code annotations containing back-references to E78.1

Back-references to E78

• Type 2 Excludes: E88.0 Disorders of plasma-protein metabolism, not elsewhere classified ("disorder of lipoprotein metabolism (E78.-)")
• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E78.1

• Dyslipidemia › elevated fasting triglycerides
• Elevated, elevation › fasting triglycerides
• Elevated, elevation › triglycerides
• Findings, abnormal, inconclusive, without diagnosis › triglycerides › high
• Frederickson's hyperlipoproteinemia, type › IV
• High › triglycerides
• Hyperglyceridemia (endogenous) (essential) (familial) (hereditary) (pure)
• Hyperlipemia, hyperlipidemia › group › B
• Hyperlipoproteinemia › Fredrickson's type › IV
• Hyperlipoproteinemia › very-low-density-lipoprotein-type (VLDL)
• Hyperprebetalipoproteinemia (familial)
• Hypertriglyceridemia, essential
• Lipoproteinemia › hyper-pre-beta
• Prebetalipoproteinemia (acquired) (essential) (familial) (hereditary) (primary) (secondary)
• Very-low-density-lipoprotein-type (VLDL) hyperlipoproteinemia
• Xanthoma (s), xanthomatosis (primary) (familial) (hereditary) › with › hyperlipoproteinemia › Type IV

Nearby codes

• E78.00 Pure hypercholesterolemia, unspecified
• E78.01 Familial hypercholesterolemia
• E78.010 Homozygous familial hypercholesterolemia [HoFH]
• E78.011 Heterozygous familial hypercholesterolemia [HeFH]
• E78.019 Familial hypercholesterolemia, unspecified
• E78.1 Pure hyperglyceridemia (this code)
• E78.2 Mixed hyperlipidemia
• E78.3 Hyperchylomicronemia
• E78.4 Other hyperlipidemia
• E78.41 Elevated Lipoprotein(a)
• E78.49 Other hyperlipidemia