E78.49 Other hyperlipidemia

Billable ICD-10-CM code, FY2026.

Applicable to

• Familial combined hyperlipidemia

Applies from E78 Disorders of lipoprotein metabolism and other lipidemias

Excludes1 (never code together)

• sphingolipidosis (E75.0-E75.3)

Risk adjustment (HCC)

• RxHCC V08: HCC 47 — Disorders of Lipoid Metabolism

MS-DRG index

Defines the logic of DRG(s) 642 in MDC 10.

Code annotations containing back-references to E78.49

Back-references to E78.49

• Type 1 Excludes: E78.2 Mixed hyperlipidemia ("familial combined hyperlipidemia (E78.49)")

Back-references to E78

• Type 2 Excludes: E88.0 Disorders of plasma-protein metabolism, not elsewhere classified ("disorder of lipoprotein metabolism (E78.-)")
• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E78.49

• Hyperlipemia, hyperlipidemia › combined › familial
• Hyperlipemia, hyperlipidemia › specified NEC

Nearby codes

• E78.1 Pure hyperglyceridemia
• E78.2 Mixed hyperlipidemia
• E78.3 Hyperchylomicronemia
• E78.4 Other hyperlipidemia
• E78.41 Elevated Lipoprotein(a)
• E78.49 Other hyperlipidemia (this code)
• E78.5 Hyperlipidemia, unspecified
• E78.6 Lipoprotein deficiency
• E78.7 Disorders of bile acid and cholesterol metabolism
• E78.70 Disorder of bile acid and cholesterol metabolism, unspecified
• E78.71 Barth syndrome