E88.819 Insulin resistance, unspecified

Billable ICD-10-CM code, FY2026.

Applies from E88 Other and unspecified metabolic disorders

Excludes1 (never code together)

• histiocytosis X (chronic) (C96.6)

Use additional code

• codes for associated conditions

Applies from E88.81 Metabolic syndrome and other insulin resistance

Use additional code

• codes for associated manifestations, such as:
• obesity (E66.-)

MS-DRG index

Defines the logic of DRG(s) 642 in MDC 10.

Code annotations containing back-references to E88.819

Back-references to E88.81

• Use Additional: O26.89 Other specified pregnancy related conditions ("code, if applicable, to identify specific condition such as insulin resistance (E88.81-)")
• Type 1 Excludes: R73.0 Abnormal glucose ("dysmetabolic syndrome X (E88.81-)")

Back-references to E88

• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E88.819

• Resistance, resistant (to) › insulin

Nearby codes

• E88.8 Other specified metabolic disorders
• E88.81 Metabolic syndrome and other insulin resistance
• E88.810 Metabolic syndrome
• E88.811 Insulin resistance syndrome, Type A
• E88.818 Other insulin resistance
• E88.819 Insulin resistance, unspecified (this code)
• E88.82 Obesity due to disruption of MC4R pathway
• E88.89 Other specified metabolic disorders
• E88.9 Metabolic disorder, unspecified
• E88.A Wasting disease (syndrome) due to underlying condition