E88.9 Metabolic disorder, unspecified

Billable ICD-10-CM code, FY2026.

Applies from E88 Other and unspecified metabolic disorders

Excludes1 (never code together)

• histiocytosis X (chronic) (C96.6)

Use additional code

• codes for associated conditions

MS-DRG index

Defines the logic of DRG(s) 642 in MDC 10.

Approximate ICD-9-CM (GEMs)

• 277.9 Unspecified disorder of metabolism (approximate)

Code annotations containing back-references to E88.9

Back-references to E88

• Type 2 Excludes: G11 Hereditary ataxia ("metabolic disorders (E70-E88)")
• Code First: G63 Polyneuropathy in diseases classified elsewhere ("metabolic diseases (E70-E88)")
• Type 2 Excludes: G71 Primary disorders of muscles ("metabolic disorders (E70-E88)")
• Code First: H42 Glaucoma in diseases classified elsewhere ("specified metabolic disorder (E70-E88)")
• Type 2 Excludes: N25.0 Renal osteodystrophy ("metabolic disorders classifiable to E70-E88")
• Type 2 Excludes: N25.81 Secondary hyperparathyroidism of renal origin ("metabolic disorders classifiable to E70-E88")
• Type 1 Excludes: P59 Neonatal jaundice from other and unspecified causes ("jaundice due to inborn errors of metabolism (E70-E88)")

Diagnosis Index entries for E88.9

• Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) › in (due to) › metabolic disorder NEC
• Arthropathy › hemophilic NEC › in (due to) › metabolic disease NOS
• Arthropathy › in (due to) › metabolic disease NOS
• Cardiomyopathy (familial) (idiopathic) › metabolic
• Cataract (cortical) (immature) (incipient) › in (due to) › metabolic disease
• Complication (s) (from) (of) › metabolic
• Disease, diseased › metabolic, metabolism
• Disease, diseased › skin › due to metabolic disorder NEC
• Disorder (of) › metabolism NOS
• Disorder (of) › metabolism NOS › congenital
• Disturbance (s) › metabolism
• Disturbance (s) › metabolism › general
• Glaucoma › in (due to) › metabolic disease NOS
• Myopathy › in (due to) › metabolic disease NEC
• Neuropathy, neuropathic › peripheral (nerve) › autonomic › in (due to) › metabolic disease NEC
• Polyneuropathy (peripheral) › in (due to) › metabolic disease NEC

Nearby codes

• E88.811 Insulin resistance syndrome, Type A
• E88.818 Other insulin resistance
• E88.819 Insulin resistance, unspecified
• E88.82 Obesity due to disruption of MC4R pathway
• E88.89 Other specified metabolic disorders
• E88.9 Metabolic disorder, unspecified (this code)
• E88.A Wasting disease (syndrome) due to underlying condition