ICD-10-CM update effective October 1, 2021: 191 new codes, 25 deleted, 30 revised titles, 14 billable-status changes. Compared with FY2021 (January 1, 2021). Source: the official CDC order files.
Other ICD-10-CM releases: FY2027, FY2026, FY2025, FY2024, FY2023 (April 1, 2023), FY2023, FY2022 (April 1, 2022), FY2021 (January 1, 2021), FY2021, FY2020 (April 1, 2020), FY2020, FY2019, FY2018, FY2017.
Also in this release: ICD-10-PCS changes.
A79.82 Anaplasmosis [A. phagocytophilum]C56.3 Malignant neoplasm of bilateral ovariesC79.63 Secondary malignant neoplasm of bilateral ovariesC84.7A Anaplastic large cell lymphoma, ALK-negative, breastD55.21 Anemia due to pyruvate kinase deficiencyD55.29 Anemia due to other disorders of glycolytic enzymesD75.83 ThrombocytosisD75.838 Other thrombocytosisD75.839 Thrombocytosis, unspecifiedD89.44 Hereditary alpha tryptasemiaE75.244 Niemann-Pick disease type A/BF32.A Depression, unspecifiedF78.A Other genetic related intellectual disabilitiesF78.A1 SYNGAP1-related intellectual disabilityF78.A9 Other genetic related intellectual disabilityG04.82 Acute flaccid myelitisG44.86 Cervicogenic headacheG92.0 Immune effector cell-associated neurotoxicity syndromeG92.00 Immune effector cell-associated neurotoxicity syndrome, grade unspecifiedG92.01 Immune effector cell-associated neurotoxicity syndrome, grade 1G92.02 Immune effector cell-associated neurotoxicity syndrome, grade 2G92.03 Immune effector cell-associated neurotoxicity syndrome, grade 3G92.04 Immune effector cell-associated neurotoxicity syndrome, grade 4G92.05 Immune effector cell-associated neurotoxicity syndrome, grade 5G92.8 Other toxic encephalopathyG92.9 Unspecified toxic encephalopathyI5A Non-ischemic myocardial injury (non-traumatic)K22.81 Esophageal polypK22.82 Esophagogastric junction polypK22.89 Other specified disease of esophagusK31.A Gastric intestinal metaplasiaK31.A0 Gastric intestinal metaplasia, unspecifiedK31.A1 Gastric intestinal metaplasia without dysplasiaK31.A11 Gastric intestinal metaplasia without dysplasia, involving the antrumK31.A12 Gastric intestinal metaplasia without dysplasia, involving the body (corpus)K31.A13 Gastric intestinal metaplasia without dysplasia, involving the fundusK31.A14 Gastric intestinal metaplasia without dysplasia, involving the cardiaK31.A15 Gastric intestinal metaplasia without dysplasia, involving multiple sitesK31.A19 Gastric intestinal metaplasia without dysplasia, unspecified siteK31.A2 Gastric intestinal metaplasia with dysplasiaK31.A21 Gastric intestinal metaplasia with low grade dysplasiaK31.A22 Gastric intestinal metaplasia with high grade dysplasiaK31.A29 Gastric intestinal metaplasia with dysplasia, unspecifiedL24.A Irritant contact dermatitis due to friction or contact with body fluidsL24.A0 Irritant contact dermatitis due to friction or contact with body fluids, unspecifiedL24.A1 Irritant contact dermatitis due to salivaL24.A2 Irritant contact dermatitis due to fecal, urinary or dual incontinenceL24.A9 Irritant contact dermatitis due friction or contact with other specified body fluidsL24.B Irritant contact dermatitis related to stoma or fistulaL24.B0 Irritant contact dermatitis related to unspecified stoma or fistulaL24.B1 Irritant contact dermatitis related to digestive stoma or fistulaL24.B2 Irritant contact dermatitis related to respiratory stoma or fistulaL24.B3 Irritant contact dermatitis related to fecal or urinary stoma or fistulaM31.10 Thrombotic microangiopathy, unspecifiedM31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]M31.19 Other thrombotic microangiopathyM35.05 Sjogren syndrome with inflammatory arthritisM35.06 Sjogren syndrome with peripheral nervous system involvementM35.07 Sjogren syndrome with central nervous system involvementM35.08 Sjogren syndrome with gastrointestinal involvementM35.0A Sjogren syndrome with glomerular diseaseM35.0B Sjogren syndrome with vasculitisM35.0C Sjogren syndrome with dental involvementM45.A Non-radiographic axial spondyloarthritisM45.A0 Non-radiographic axial spondyloarthritis of unspecified sites in spineM45.A1 Non-radiographic axial spondyloarthritis of occipito-atlanto-axial regionM45.A2 Non-radiographic axial spondyloarthritis of cervical regionM45.A3 Non-radiographic axial spondyloarthritis of cervicothoracic regionM45.A4 Non-radiographic axial spondyloarthritis of thoracic regionM45.A5 Non-radiographic axial spondyloarthritis of thoracolumbar regionM45.A6 Non-radiographic axial spondyloarthritis of lumbar regionM45.A7 Non-radiographic axial spondyloarthritis of lumbosacral regionM45.A8 Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal regionM45.AB Non-radiographic axial spondyloarthritis of multiple sites in spineM54.50 Low back pain, unspecifiedM54.51 Vertebrogenic low back painM54.59 Other low back painP00.82 Newborn affected by (positive) maternal group B streptococcus (GBS) colonizationP09.1 Abnormal findings on neonatal screening for inborn errors of metabolismP09.2 Abnormal findings on neonatal screening for congenital endocrine diseaseP09.3 Abnormal findings on neonatal screening for congenital hematologic disordersP09.4 Abnormal findings on neonatal screening for cystic fibrosisP09.5 Abnormal findings on neonatal screening for critical congenital heart diseaseP09.6 Abnormal findings on neonatal screening for neonatal hearing lossP09.8 Other abnormal findings on neonatal screeningP09.9 Abnormal findings on neonatal screening, unspecifiedR05.1 Acute coughR05.2 Subacute coughR05.3 Chronic coughR05.4 Cough syncopeR05.8 Other specified coughR05.9 Cough, unspecifiedR35.81 Nocturnal polyuriaR35.89 Other polyuriaR45.88 Nonsuicidal self-harmR63.30 Feeding difficulties, unspecifiedR63.31 Pediatric feeding disorder, acuteR63.32 Pediatric feeding disorder, chronicR63.39 Other feeding difficultiesR79.83 Abnormal findings of blood amino-acid levelS06.A Traumatic brain compression and herniationS06.A0 Traumatic brain compression without herniationS06.A0XA Traumatic brain compression without herniation, initial encounterS06.A0XD Traumatic brain compression without herniation, subsequent encounterS06.A0XS Traumatic brain compression without herniation, sequelaS06.A1 Traumatic brain compression with herniationS06.A1XA Traumatic brain compression with herniation, initial encounterS06.A1XD Traumatic brain compression with herniation, subsequent encounterS06.A1XS Traumatic brain compression with herniation, sequelaT40.71 Poisoning by, adverse effect of and underdosing of cannabis (derivatives)T40.711 Poisoning by cannabis, accidental (unintentional)T40.711A Poisoning by cannabis, accidental (unintentional), initial encounterT40.711D Poisoning by cannabis, accidental (unintentional), subsequent encounterT40.711S Poisoning by cannabis, accidental (unintentional), sequelaT40.712 Poisoning by cannabis, intentional self-harmT40.712A Poisoning by cannabis, intentional self-harm, initial encounterT40.712D Poisoning by cannabis, intentional self-harm, subsequent encounterT40.712S Poisoning by cannabis, intentional self-harm, sequelaT40.713 Poisoning by cannabis, assaultT40.713A Poisoning by cannabis, assault, initial encounterT40.713D Poisoning by cannabis, assault, subsequent encounterT40.713S Poisoning by cannabis, assault, sequelaT40.714 Poisoning by cannabis, undeterminedT40.714A Poisoning by cannabis, undetermined, initial encounterT40.714D Poisoning by cannabis, undetermined, subsequent encounterT40.714S Poisoning by cannabis, undetermined, sequelaT40.715 Adverse effect of cannabisT40.715A Adverse effect of cannabis, initial encounterT40.715D Adverse effect of cannabis, subsequent encounterT40.715S Adverse effect of cannabis, sequelaT40.716 Underdosing of cannabisT40.716A Underdosing of cannabis, initial encounterT40.716D Underdosing of cannabis, subsequent encounterT40.716S Underdosing of cannabis, sequelaT40.72 Poisoning by, adverse effect of and underdosing of synthetic cannabinoidsT40.721 Poisoning by synthetic cannabinoids, accidental (unintentional)T40.721A Poisoning by synthetic cannabinoids, accidental (unintentional), initial encounterT40.721D Poisoning by synthetic cannabinoids, accidental (unintentional), subsequent encounterT40.721S Poisoning by synthetic cannabinoids, accidental (unintentional), sequelaT40.722 Poisoning by synthetic cannabinoids, intentional self-harmT40.722A Poisoning by synthetic cannabinoids, intentional self-harm, initial encounterT40.722D Poisoning by synthetic cannabinoids, intentional self-harm, subsequent encounterT40.722S Poisoning by synthetic cannabinoids, intentional self-harm, sequelaT40.723 Poisoning by synthetic cannabinoids, assaultT40.723A Poisoning by synthetic cannabinoids, assault, initial encounterT40.723D Poisoning by synthetic cannabinoids, assault, subsequent encounterT40.723S Poisoning by synthetic cannabinoids, assault, sequelaT40.724 Poisoning by synthetic cannabinoids, undeterminedT40.724A Poisoning by synthetic cannabinoids, undetermined, initial encounterT40.724D Poisoning by synthetic cannabinoids, undetermined, subsequent encounterT40.724S Poisoning by synthetic cannabinoids, undetermined, sequelaT40.725 Adverse effect of synthetic cannabinoidsT40.725A Adverse effect of synthetic cannabinoids, initial encounterT40.725D Adverse effect of synthetic cannabinoids, subsequent encounterT40.725S Adverse effect of synthetic cannabinoids, sequelaT40.726 Underdosing of synthetic cannabinoidsT40.726A Underdosing of synthetic cannabinoids, initial encounterT40.726D Underdosing of synthetic cannabinoids, subsequent encounterT40.726S Underdosing of synthetic cannabinoids, sequelaT80.82 Complication of immune effector cellular therapyT80.82XA Complication of immune effector cellular therapy, initial encounterT80.82XD Complication of immune effector cellular therapy, subsequent encounterT80.82XS Complication of immune effector cellular therapy, sequelaY35.899 Legal intervention involving other specified means, unspecified person injuredY35.899A Legal intervention involving other specified means, unspecified person injured, initial encounterY35.899D Legal intervention involving other specified means, unspecified person injured, subsequent encounterY35.899S Legal intervention involving other specified means, unspecified person injured, sequelaZ55.5 Less than a high school diplomaZ58 Problems related to physical environmentZ58.6 Inadequate drinking-water supplyZ59.00 Homelessness unspecifiedZ59.01 Sheltered homelessnessZ59.02 Unsheltered homelessnessZ59.41 Food insecurityZ59.48 Other specified lack of adequate foodZ59.81 Housing instability, housedZ59.811 Housing instability, housed, with risk of homelessnessZ59.812 Housing instability, housed, homelessness in past 12 monthsZ59.819 Housing instability, housed unspecifiedZ59.89 Other problems related to housing and economic circumstancesZ71.85 Encounter for immunization safety counselingZ91.014 Allergy to mammalian meatsZ91.51 Personal history of suicidal behaviorZ91.52 Personal history of nonsuicidal self-harmZ92.85 Personal history of cellular therapyZ92.850 Personal history of Chimeric Antigen Receptor T-cell therapyZ92.858 Personal history of other cellular therapyZ92.859 Personal history of cellular therapy, unspecifiedZ92.86 Personal history of gene therapyU09 Post COVID-19 conditionU09.9 Post COVID-19 condition, unspecifiedT40.7X Poisoning by, adverse effect of and underdosing of cannabis (derivatives)T40.7X1 Poisoning by cannabis (derivatives), accidental (unintentional)T40.7X1A Poisoning by cannabis (derivatives), accidental (unintentional), initial encounterT40.7X1D Poisoning by cannabis (derivatives), accidental (unintentional), subsequent encounterT40.7X1S Poisoning by cannabis (derivatives), accidental (unintentional), sequelaT40.7X2 Poisoning by cannabis (derivatives), intentional self-harmT40.7X2A Poisoning by cannabis (derivatives), intentional self-harm, initial encounterT40.7X2D Poisoning by cannabis (derivatives), intentional self-harm, subsequent encounterT40.7X2S Poisoning by cannabis (derivatives), intentional self-harm, sequelaT40.7X3 Poisoning by cannabis (derivatives), assaultT40.7X3A Poisoning by cannabis (derivatives), assault, initial encounterT40.7X3D Poisoning by cannabis (derivatives), assault, subsequent encounterT40.7X3S Poisoning by cannabis (derivatives), assault, sequelaT40.7X4 Poisoning by cannabis (derivatives), undeterminedT40.7X4A Poisoning by cannabis (derivatives), undetermined, initial encounterT40.7X4D Poisoning by cannabis (derivatives), undetermined, subsequent encounterT40.7X4S Poisoning by cannabis (derivatives), undetermined, sequelaT40.7X5 Adverse effect of cannabis (derivatives)T40.7X5A Adverse effect of cannabis (derivatives), initial encounterT40.7X5D Adverse effect of cannabis (derivatives), subsequent encounterT40.7X5S Adverse effect of cannabis (derivatives), sequelaT40.7X6 Underdosing of cannabis (derivatives)T40.7X6A Underdosing of cannabis (derivatives), initial encounterT40.7X6D Underdosing of cannabis (derivatives), subsequent encounterT40.7X6S Underdosing of cannabis (derivatives), sequelaF32 Depressive episode (was: Major depressive disorder, single episode)G71.20 Congenital myopathy, unspecified (was: Congenital myopathy, unspecifed)M35.0 Sjogren syndrome (was: Sicca syndrome [Sjogren])M35.00 Sjogren syndrome, unspecified (was: Sicca syndrome, unspecified)M35.01 Sjogren syndrome with keratoconjunctivitis (was: Sicca syndrome with keratoconjunctivitis)M35.02 Sjogren syndrome with lung involvement (was: Sicca syndrome with lung involvement)M35.03 Sjogren syndrome with myopathy (was: Sicca syndrome with myopathy)M35.04 Sjogren syndrome with tubulo-interstitial nephropathy (was: Sicca syndrome with tubulo-interstitial nephropathy)M35.09 Sjogren syndrome with other organ involvement (was: Sicca syndrome with other organ involvement)T63.61 Toxic effect of contact with Portuguese Man-o-war (was: Toxic effect of contact with Portugese Man-o-war)T63.611 Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional) (was: Toxic effect of contact with Portugese Man-o-war, accidental (unintentional))T63.611A Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional), initial encounter (was: Toxic effect of contact with Portugese Man-o-war, accidental (unintentional), initial encounter)T63.611D Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional), subsequent encounter (was: Toxic effect of contact with Portugese Man-o-war, accidental (unintentional), subsequent encounter)T63.611S Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional), sequela (was: Toxic effect of contact with Portugese Man-o-war, accidental (unintentional), sequela)T63.612 Toxic effect of contact with Portuguese Man-o-war, intentional self-harm (was: Toxic effect of contact with Portugese Man-o-war, intentional self-harm)T63.612A Toxic effect of contact with Portuguese Man-o-war, intentional self-harm, initial encounter (was: Toxic effect of contact with Portugese Man-o-war, intentional self-harm, initial encounter)T63.612D Toxic effect of contact with Portuguese Man-o-war, intentional self-harm, subsequent encounter (was: Toxic effect of contact with Portugese Man-o-war, intentional self-harm, subsequent encounter)T63.612S Toxic effect of contact with Portuguese Man-o-war, intentional self-harm, sequela (was: Toxic effect of contact with Portugese Man-o-war, intentional self-harm, sequela)T63.613 Toxic effect of contact with Portuguese Man-o-war, assault (was: Toxic effect of contact with Portugese Man-o-war, assault)T63.613A Toxic effect of contact with Portuguese Man-o-war, assault, initial encounter (was: Toxic effect of contact with Portugese Man-o-war, assault, initial encounter)T63.613D Toxic effect of contact with Portuguese Man-o-war, assault, subsequent encounter (was: Toxic effect of contact with Portugese Man-o-war, assault, subsequent encounter)T63.613S Toxic effect of contact with Portuguese Man-o-war, assault, sequela (was: Toxic effect of contact with Portugese Man-o-war, assault, sequela)T63.614 Toxic effect of contact with Portuguese Man-o-war, undetermined (was: Toxic effect of contact with Portugese Man-o-war, undetermined)T63.614A Toxic effect of contact with Portuguese Man-o-war, undetermined, initial encounter (was: Toxic effect of contact with Portugese Man-o-war, undetermined, initial encounter)T63.614D Toxic effect of contact with Portuguese Man-o-war, undetermined, subsequent encounter (was: Toxic effect of contact with Portugese Man-o-war, undetermined, subsequent encounter)T63.614S Toxic effect of contact with Portuguese Man-o-war, undetermined, sequela (was: Toxic effect of contact with Portugese Man-o-war, undetermined, sequela)Z59.4 Lack of adequate food (was: Lack of adequate food and safe drinking water)Z68.30 Body mass index [BMI] 30.0-30.9, adult (was: Body mass index [BMI]30.0-30.9, adult)Z68.41 Body mass index [BMI] 40.0-44.9, adult (was: Body mass index [BMI]40.0-44.9, adult)Z92.25 Personal history of immunosuppression therapy (was: Personal history of immunosupression therapy)D55.2 Anemia due to disorders of glycolytic enzymes: now a non-billable headerF78 Other intellectual disabilities: now a non-billable headerG92 Toxic encephalopathy: now a non-billable headerK22.8 Other specified diseases of esophagus: now a non-billable headerM31.1 Thrombotic microangiopathy: now a non-billable headerM54.5 Low back pain: now a non-billable headerP09 Abnormal findings on neonatal screening: now a non-billable headerR05 Cough: now a non-billable headerR35.8 Other polyuria: now a non-billable headerR63.3 Feeding difficulties: now a non-billable headerZ59.0 Homelessness: now a non-billable headerZ59.4 Lack of adequate food: now a non-billable headerZ59.8 Other problems related to housing and economic circumstances: now a non-billable headerZ91.5 Personal history of self-harm: now a non-billable header