T45.1 Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs

Non-billable header with 1 child codes.

Excludes1 (never code together)

• poisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugs (T45.A)
• poisoning by, adverse effect of and underdosing of tamoxifen (T38.6)

Applies from T45 Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified

7th character note

• The appropriate 7th character is to be added to each code from category T45

7th character required

• A — initial encounter
• D — subsequent encounter
• S — sequela

Codes under T45.1

• T45.1X Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs

Code annotations containing back-references to T45.1

Back-references to T45.1

• Type 1 Excludes: T36 Poisoning by, adverse effect of and underdosing of systemic antibiotics ("antineoplastic antibiotics (T45.1-)")
• Type 1 Excludes: T37.5 Poisoning by, adverse effect of and underdosing of antiviral drugs ("cytarabine (T45.1-)")
• Type 1 Excludes: T45.A Poisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugs ("poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drug (T45.1)")

Back-references to T45

• Use Additional: D46 Myelodysplastic syndromes ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D52.1 Drug-induced folate deficiency anemia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D59.0 Drug-induced autoimmune hemolytic anemia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D59.2 Drug-induced nonautoimmune hemolytic anemia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D59.39 Other hemolytic-uremic syndrome ("code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D61.1 Drug-induced aplastic anemia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: D64.2 Secondary sideroblastic anemia due to drugs and toxins ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: D64.2 Secondary sideroblastic anemia due to drugs and toxins ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D70.2 Other drug-induced agranulocytosis ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D72.12 Drug rash with eosinophilia and systemic symptoms syndrome ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: D84.821 Immunodeficiency due to drugs ("code for adverse effect if applicable, to identify adverse effect of drug (T36-T50 with fifth or six character 5)")
• Use Additional: D89.3 Immune reconstitution syndrome ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: E03.2 Hypothyroidism due to medicaments and other exogenous substances ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: E03.2 Hypothyroidism due to medicaments and other exogenous substances ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E06.4 Drug-induced thyroiditis ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: E09 Drug or chemical induced diabetes mellitus ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: E09 Drug or chemical induced diabetes mellitus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E16.0 Drug-induced hypoglycemia without coma ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E22.1 Hyperprolactinemia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E23.1 Drug-induced hypopituitarism ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E24.2 Drug-induced Cushing's syndrome ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E25.8 Other adrenogenital disorders ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E27.3 Drug-induced adrenocortical insufficiency ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E28.0 Estrogen excess ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E28.1 Androgen excess ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E29.1 Testicular hypofunction ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E61 Deficiency of other nutrient elements ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: E66.1 Drug-induced obesity ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: F02 Dementia in other diseases classified elsewhere ("intoxications (T36-T65)")
• Use Additional: G21.19 Other drug induced secondary parkinsonism ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G24.0 Drug induced dystonia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G25.1 Drug-induced tremor ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G25.3 Myoclonus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G25.4 Drug-induced chorea ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G25.61 Drug induced tics ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G25.7 Other and unspecified drug induced movement disorders ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G40.5 Epileptic seizures related to external causes ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G43 Migraine ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G44.4 Drug-induced headache, not elsewhere classified ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G62.0 Drug-induced polyneuropathy ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G71.14 Drug induced myotonia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: G72.0 Drug-induced myopathy ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: G92.8 Other toxic encephalopathy ("poisoning due to drug or toxin, if applicable, (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: G92.8 Other toxic encephalopathy ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: G92.9 Unspecified toxic encephalopathy ("poisoning due to drug or toxin, if applicable, (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: G92.9 Unspecified toxic encephalopathy ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: H21.81 Floppy iris syndrome ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: H26.3 Drug-induced cataract ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: H35.38 Toxic maculopathy ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: H35.38 Toxic maculopathy ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: H40.6 Glaucoma secondary to drugs ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: H91.0 Ototoxic hearing loss ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: H91.0 Ototoxic hearing loss ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: I42.7 Cardiomyopathy due to drug and external agent ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: I42.7 Cardiomyopathy due to drug and external agent ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: I47.21 Torsades de pointes ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: I95.2 Hypotension due to drugs ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: J70.2 Acute drug-induced interstitial lung disorders ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: J70.3 Chronic drug-induced interstitial lung disorders ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: J70.4 Drug-induced interstitial lung disorders, unspecified ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: J84.89 Other specified interstitial pulmonary diseases ("code, for adverse effect, to identify drug (T36-T50 with fifth or sixth character 5), if drug-induced")
• Use Additional: K12.32 Oral mucositis (ulcerative) due to other drugs ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: K22.1 Ulcer of esophagus ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: K22.1 Ulcer of esophagus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: K52.1 Toxic gastroenteritis and colitis ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: K59.03 Drug induced constipation ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: K71 Toxic liver disease ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: K71 Toxic liver disease ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: K85.3 Drug induced acute pancreatitis ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L10.5 Drug-induced pemphigus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L12.31 Epidermolysis bullosa due to drug ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L23.3 Allergic contact dermatitis due to drugs in contact with skin ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L24.4 Irritant contact dermatitis due to drugs in contact with skin ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L25.1 Unspecified contact dermatitis due to drugs in contact with skin ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L27.0 Generalized skin eruption due to drugs and medicaments taken internally ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L27.1 Localized skin eruption due to drugs and medicaments taken internally ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L29.81 Cholestatic pruritus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L43.2 Lichenoid drug reaction ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L51 Erythema multiforme ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: L53.0 Toxic erythema ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: L53.0 Toxic erythema ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L56.0 Drug phototoxic response ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L56.1 Drug photoallergic response ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L64.0 Drug-induced androgenic alopecia ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L65 Other nonscarring hair loss ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L71 Rosacea ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: L93 Lupus erythematosus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M1A.2 Drug-induced chronic gout ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M10.2 Drug-induced gout ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M32.0 Drug-induced systemic lupus erythematosus ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: M34.2 Systemic sclerosis induced by drug and chemical ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: M34.2 Systemic sclerosis induced by drug and chemical ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M80.8 Other osteoporosis with current pathological fracture ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M81.8 Other osteoporosis without current pathological fracture ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M83.5 Other drug-induced osteomalacia in adults ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Use Additional: M87.1 Osteonecrosis due to drugs ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")
• Code First: P58.4 Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn ("poisoning due to drug or toxin, if applicable (T36-T65 with fifth or sixth character 1-4)")
• Use Additional: P58.4 Neonatal jaundice due to drugs or toxins transmitted from mother or given to newborn ("code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)")

Nearby codes

• T45.0X5S Adverse effect of antiallergic and antiemetic drugs, sequela
• T45.0X6 Underdosing of antiallergic and antiemetic drugs
• T45.0X6A Underdosing of antiallergic and antiemetic drugs, initial encounter
• T45.0X6D Underdosing of antiallergic and antiemetic drugs, subsequent encounter
• T45.0X6S Underdosing of antiallergic and antiemetic drugs, sequela
• T45.1 Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs (this code)
• T45.1X Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugs
• T45.1X1 Poisoning by antineoplastic and immunosuppressive drugs, accidental (unintentional)
• T45.1X1A Poisoning by antineoplastic and immunosuppressive drugs, accidental (unintentional), initial encounter
• T45.1X1D Poisoning by antineoplastic and immunosuppressive drugs, accidental (unintentional), subsequent encounter
• T45.1X1S Poisoning by antineoplastic and immunosuppressive drugs, accidental (unintentional), sequela